Alzheimer’s disease and macular degeneration concerns with Entresto

Three academic physicians, writing in an editorial in the Journal of the American Medical Association, raised serious (but theoretical) concerns about the risk of Alzheimer’s disease and macular degeneration with long-term use of the new heart failure drug, valsartan/sacubitril (Entresto, Novartis). Here is the translation: Sacubitril is a drug that inhibits neprilysin, which is an… Continue reading Alzheimer’s disease and macular degeneration concerns with Entresto

Cycling Wed: Rest is best…

Dear Cyclists (or other endurance athletes), Since your heart—a muscle, like any other muscle in your body—is at the crux of cycling performance, I thought a story on a common heart condition might be helpful. The story involves a common cardiac condition called “tachycardia-mediated cardiomyopathy.” Now hold on a minute; don’t click away yet.  Let… Continue reading Cycling Wed: Rest is best…